New Treatments for Acute Rheumatic Fever Helen D. Jones, MD

New Treatments for Acute Rheumatic Fever

Helen D. Jones, MD

Volume 2530, No 8, pp. 4391-4455, January 22, 2008

The etiology of acute rheumatic fever, ARF, is an immune response to group A beta hemolytic streptococcal infection. It only occurs with the throat infection. It does not occur following the skin infections with the same organism. In order to make the diagnosis you have to have the Jones criteria but you also have to have evidence of recent group A strep infection; either positive throat culture, rapid antigen test or a rising streptococcal antibody titer, usually an ASO titer. If you have this then you need to meet the Jones criteria and you need to have two major or one major and two minor criteria. There are five major criteria; carditis, polyarthritis, chorea, erythema marginatum, or subcutaneous nodules. People often think that fever is a major criteria because it’s called rheumatic fever, but fever is not a major criteria. It’s a minor criteria, as is arthralgia, which is joint pain without swelling. Prolonged P-R interval is also a minor criteria as well as elevated sed rate of C-Reactive protein.
http://www.medical-library.org/journals/secure/0401/rheumatic_fever.htm

اسم المستخدم: 1929
كلمة السر:1929

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